Best Joint Supplements for Athletes: From Runners to Bodybuilders

Are you an athlete, runner, or bodybuilder searching for the ultimate solution to joint discomfort?

You're not alone. The quest for the best joint supplements for athletes is more than just a trend; it's a crucial part of maintaining peak physical performance and overall well-being. In this comprehensive guide, we dive into the world of joint supplements, tailored specifically for athletes like you.

Our approach is simple yet thorough: we provide clear, expert-backed insights without overwhelming you with technical jargon. Whether you're a marathon runner feeling the toll of those extra miles, a bodybuilder pushing your limits, or an athlete seeking to optimize your health, we understand your unique needs. This article is your gateway to discovering supplements that not only promise relief but also cater to your specific athletic lifestyle.

We've consulted industry experts to bring you a list that's not just about the 'best' in name, but the best in effectiveness, quality, and safety. So, let's embark on this journey together, where you'll find not just products, but solutions that resonate with your goals and health aspirations. Welcome to a community where your pursuit of fitness and wellness is understood and supported.

Understanding Joint Health in Athletes

Multiple factors could explain the high prevalence of musculoskeletal injuries among athletes, especially competitive-level ones. Sports medicine experts claim that athletes who frequently get injured or perform poorly typically single out three principal factors :

Muscle imbalances

A muscular imbalance is an irregularity in size, strength, or symmetry among muscle groups. Repetitive movements, poor posture, and overtraining can cause muscle imbalances. Things can go wrong when the body does not fully use each of its muscles, which can be forced to over-compensate, ultimately leading to more compensation and subsequent injuries.

Core instability

The core is the body's center and stabilizes the trunk while the arms and legs move during functional movements. Core instability occurs when joint supporting structures fail to maintain adequate joint congruity, leading to poor physical performance, chronic pain, and joint dysfunction or instability.

Poor neuromuscular control

Neuromuscular control is the ability to control movement through coordinated muscle activity. If a person is tired or fatigued, this may predispose them to poor neuromuscular control patterns, leading to injury, especially in the extremities.

One study found that the incidence of injuries among athletes is three to five times higher than in the general population.

Common Joint Injuries and Issues In Athletes

Joint supplements for athletes

  • Lower back injuries - Athletes are prone to various lower back injuries like herniated intervertebral discs, spondylolysis, and strained back muscles. These injuries are often a result of heavy lifting, hyperextension, poor form, and insufficient rest.
  • Overuse injuries - Overuse injuries of the knee occur after performing activities that require repetitive motion. Among athletes, such injuries occur during repetitive movements like throwing, running, and swimming and not having sufficient rest afterward.
  • Rotator cuff tears - Rotator cuff tears occur when the shoulder joints suffer wear and, resulting in them becoming weaker making them more prone to injury. Those who play baseball, tennis, basketball, golf, swimming, football, lacrosse, and ice hockey are often prone to this type of injury.
  • Knee-related injuries - Knee injuries like ACL tear, meniscus tear, patellar tendonitis, bone fractures, sprains, and dislocations are common among most athletes, often a result of force trauma. 

Evaluating Joint Supplements for Athletes

Criteria for Choosing the Best Supplements

You should consider some factors when settling for a joint supplement to aid your mobility during athletic performance.

    • Ingredient profile - The ingredient blend can make or break a product’s efficacy. One should always check a product's label or research the ingredient profile to ensure compatibility with all its ingredients and if they’re potent enough. 
    • Bioavailability - High bioavailability increases the chance that the supplement is utilized and absorbed by the body. Certain ingredients are more bioavailable or can help in increasing absorption.
    • Safety and side effects - Avoid supplements with ingredients you may be allergic to. Steer clear of products with additives, preservatives, or unhealthy ingredients. Make sure to get supplements that have third-party quality/purity testing certifications.

Types of Joint Supplements


Glucosamine is a naturally occurring amino acid with anti-inflammatory properties that help relieve musculoskeletal pain and stiffness, improve muscle function, and increase mobility, making it a staple for treating osteoarthritis, particularly knee osteoarthritis.


Chondroitin is made of amino acids and glucosamine sulfate. It helps protect the cartilage in joints, prevents it from suffering further damage, provides pain relief, and inhibits enzymes that contribute to cartilage degradation.

Methylsulfonylmethane (MSM)

Methylsulfonylmethane (MSM) is a sulfur-rich compound in plants, animals, and humans. Sulfur-containing compounds like methylsulfonylmethane have potent anti-inflammatory properties that treat osteoarthritis, rheumatoid arthritis, tendonitis, and tenosynovitis. 


Thanks to its active ingredient, curcumin, turmeric has powerful antioxidant and anti-inflammatory properties, which could help ease osteoarthritis pain and resolve many musculoskeletal problems, often resulting from inflammatory conditions and oxidative stress. 


Bromelain is a combination of proteolytic enzymes extracted from the stem and fruit of pineapples. Its high bioavailability and anti-inflammatory effects help reduce arthritis symptoms and improve joint function, making it a better and safer treatment for osteoarthritis


Ginger has powerful medicinal purposes thanks to its active compounds, such as gingerols, shogaols, and parasols, which have powerful anti-inflammatory properties that are especially helpful for combating symptoms like rheumatoid arthritis, osteoarthritis, and immobility.


Boswellia is an herbal extract from the Boswellia serrata tree whose sap, bark, and other plant parts have anti-inflammatory properties, making them effective for inflammatory conditions like rheumatoid arthritis, osteoarthritis, and cartilage damage and degradation

Fish Oil

Fish oils come from fatty or oily fish. They contain omega-3 fatty acids contains anti-inflammatory properties that improve some people's symptoms of rheumatoid arthritis, such as joint stiffness, tenderness, and pain

Hyaluronic Acid

A popular ingredient in skincare products to improve skin health, hyaluronic acid also promotes and facilitates cell and tissue growth, resulting in joint cartilage and bone growth and development. It also provides quick and effective pain relief from sore joints.

Top Joint Supplements for Athletes

Physio Flex Pro for athletes

Best Overall Athletic Joint Supplements

Most experts agree that combining the following ingredients benefits athletes best since they work synergistically in targeting all joint health problems to achieve optimal athletic performance.

    • Turmeric is a popular spice rich in anti-inflammatory and antioxidant properties that block harmful COX-2 enzymes contributing to joint problems.
    • Bromelain - Repairs connective tissues and produces more synovial fluid to keep the joints lubricated to restore mobility and flexibility.
    • Glucosamine – Benefits the cartilage cells, strengthens connective tissues, and promotes the production of joint-lubricating synovial fluid. 
    • Chondroitin – Maintains the integrity of the cartilage, keeping it well-lubricated, relaxed, and shock-absorbent.
    • Methylsulfonylmethane (MSM) – Helps reduce joint pain and swelling and improve function in people with osteoarthritis.
    • Selenium - Selenium is best known for its antioxidant and anti-inflammatory properties that fight against oxidative stress and damage, which affects both cartilage and joints.
    • Ginger - Ginger has strong analgesic properties and helps reduce the activity of chemical substances contributing to joint inflammation.  
    • Bioperine - Highly prized for its anti-inflammatory properties that relieve joint pain, this patented piperine extract also stands out for increasing a supplement’s bioavailability. 

A supplement like Physio Flex Pro has all of these ingredients in measured recommended doses to best support the protection of key connective tissues, cartilage integrity, and healthy joints for better mobility and flexibility.

Best Joint Supplements for Runners

For runners, lateral knee pain is an all-too-common problem; this type of pain is caused by things like lateral collateral ligament injury, iliotibial band syndrome, osteoarthritis, or simply through repetitive activity. The pain is intermittent, sometimes accompanied by a tightening or burning sensation, which can dampen a runner’s mobility.

The following substances are especially beneficial for runners:

  • Omega 3 fatty acids - Omega-3 fatty acids reduce inflammation, particularly in the joints, and improve symptoms of rheumatoid arthritis, such as morning stiffness, tender/swollen joints, and joint pains.
  • Zinc – Zinc benefits joint health through its anti-inflammatory properties and ability to promote collagen synthesis.
  • Magnesium – Magnesium is essential to overall musculoskeletal health and prevents inflammatory conditions. 
  • Vitamin E – Vitamin E has high antioxidant properties that protect cells from free radicals in the body and fight oxidative stress in the joints.

Pairing these supplements with Physio Flex Pro can create a synergistic effect and may even increase its bioavailability, thanks to its bioperine content.

An ideal joint supplement stack comes in the form of our Joint Freedom Vitality Bundle of Biorixil Omega 3's & Physio Flex Pro.

Best Joint Supplements for Bodybuilders

Without proper warmup, form, or rest, bodybuilders can be prone to experiencing pain in their back, neck, and shoulders, and can put extra strain and stress on the joints in those areas.

Taking pre-workout supplements with these ingredients conditions and prepares your body with enough energy to carry out weightlifting exercises successfully.

  • Creatine –  Enhances athletic performance, improves muscle strength and power, and maintains muscle mass.
  • Protein – Protein provides a steady supply of essential amino acids and branched-chain amino acids to prevent muscle breakdown and provide ample nutrition to last through the workout.
  • Taurine - Aside from being an energy source, taurine promotes muscle recovery by reducing post-workout muscle soreness and influencing electrolyte utilization.

Taking Physio Flex Pro before a workout can help reinforce your joints and keep you mobile and flexible enough for each rep x set you make.

Incorporating Supplements into an Athletic Regimen

Dosage and Timing

Always follow the recommended dosage on the supplement packaging or as your healthcare provider recommends. Most joint supplements require eating a meal before intake to increase absorption and prevent/mitigate side effects.

Since athletes usually eat 2 or 3 hours before a workout, you can take the supplement around that time for it to take effect.

Taking more than the recommended dosage doesn't increase its effectiveness and can lead to side effects.

Combining Supplements with Diet and Lifestyle Changes

Taking supplements complements healthy habits like eating a healthy diet and observing lifestyle changes and serves to increase the efficiency of the joint recovery regimen.

Safety and Side Effects

Joint supplements are usually safe and don’t normally cause side effects. However, in the rare instances that they do, the following are commonly reported:

  • Nausea
  • Headaches
  • Stomach troubles
  • Vomiting
  • Drowsiness

Certain ingredients may interact with any medication you might be currently taking:


  • Acetaminophen
  • Warfarin


  • Anticoagulants
  • Warfarin

Methylsulfonylmethane (MSM) 

  • No known interactions

Omega-3 fatty acids

  • Blood thinning medications
  • Corticosteroids
  • Cholesterol-lowering medications
  • Cyclosporine
  • Non-steroidal inflammatory drugs (NSAIDs)


  • Antibiotics
  • Anticoagulants
  • Sedatives


  • Anticoagulants
  • Anti-diabetes medications
  • Anti-tumor medications
  • Anti-cancer medications
  • Estrogen

Hyaluronic Acid

  • No known interactions


  • Antacids
  • Birth control pills
  • Chemotherapy drugs
  • Corticosteroids
  • Cholesterol-lowering statin drugs
  • Niacin


  • No known interactions


  • Antibiotics 
  • Nitrofurantoin (macrodandin).

Vitamin D

  • Aluminum
  • Anticonvulsants
  • Calcipotriene 
  • Cholesterol medications
  • Digoxin 
  • Diltiazem 
  • Laxatives
  • Orlistat
  • Steroids
  • Thiazide diuretics
  • Verapamil

Frequently Asked Questions (FAQs)

Q1: How long does it take for joint supplements to show results in athletes?

A: Joint supplements may take a few weeks to a month to yield any results. However, the timeframe may vary individually since everyone has a unique response to supplements.

Q2: Can joint supplements interact with other medications commonly used by athletes?

A: Ingredients of certain supplements may interact with medications often used by athletes, such as NSAIDs, analgesics, antihypertensives, and antibiotics.

Q3: Are there any natural food sources that effectively support joint health?

A: Omega-3-rich like leafy greens, fresh fruits, fatty fish, and poultry can make a great difference to an athlete’s joint health and mobility. Foods rich in magnesium, vitamin D, and calcium help fight infection and inflammation that cause joint problems.

Drinking lots of fluids also keeps the cartilage intact and the joints lubricated.

Q4: How do joint supplement needs vary between different types of athletes (e.g., endurance vs strength athletes)?

A: Athletes are generally more likely to sustain joint injuries than the average individual, regardless of whether they’re runners, bodybuilders, sportsmen, or fitness enthusiasts. However, athletes who do high-impact activities or sports that put stress on weight-bearing joints, such as the knee, hip, or ankle, may require a more consistent regimen of highly potent joint-beneficial supplements.

Q5: Can joint supplements improve performance or just aid in recovery?

A: Research is mixed on whether joint supplements can actually improve athletic performance or speed recovery. But based on reviews from athletes taking these supplements, we can deduce that they mainly help recover flexibility and mobility without actively enhancing physical performance/stamina.


Athletes can benefit greatly from joint supplementation; joint health supplements like Physio Flex Pro can offer extra joint protection and aid post-workout musculoskeletal recovery, helping them achieve optimal physical performance.

Consulting with your healthcare provider, physical therapist, or trainer can help you get a better insight into how joint health is integral to athletic performance and how you can use supplements to your advantage.

This article focused on more high-impact sports like running and bodybuilding but we have also performed deep dives for other types of athletes. Take a look at our article that covers the best supplements for tennis elbow.

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